One of the biggest fight cards of 2025 has finally arrived. Check out these in-depth UFC 319: Du Plessis vs. Chimaev predictions and betting breakdowns.

Chimaev ripped through the competition in his first few UFC bouts, immediately making himself into a man many believed was destined for UFC gold. Chimaev has had to battle through injuries, illnesses and travel issues to finally get his crack at a title and now looks to make good when he faces du Plessis in Chicago.

The main card begins at 10 p.m. ET and is headlined by middleweight champion Dricus du Plessis defending against the undefeated Khamzat Chimaev. Fans can purchase the event for $79.99 on ESPN+ PPV. The main event walkouts are expected to take place around 12-12:30 a.m. ET.