Bird flu, also known as avian influenza or H5N1, has infected more than 130 million birds over the past two years as it threatened commercial bird operations and recently led to the first human death in the United States.

A Louisiana resident previously hospitalized with avian influenza has died, the Centers for Disease Control and Prevention announced Monday, marking the first bird flu death in the United States.

The first person to have a severe case of H5N1 bird flu in the United States has died, according to the Louisiana Department of Health.