A tour bus returning from a trip to Niagara Falls overturned in upstate New York on Friday, killing five people and injuring dozens of others, some of whom became trapped or ejected, police said. The deadly crash occurred on Interstate 90 in Pembroke, near Buffalo, according to New York State Police.

The New York State Thruway Authority reported traffic backed up in the area. WIVB-TV in Buffalo reported several Mercy Flight helicopters were requested, and some uninjured passengers were taken to the Indian Falls Fire Station.

A tour bus rolled over in a "serious mass casualty" crash on a major highway in upstate New York Friday, officials said. The collision closed all lanes on the New York State Thruway near Pembroke, around 30 miles northeast of Buffalo and 40 miles southeast of Niagara Falls, New York State Police said .