A steroid hormone called aldosterone is linked to an increased risk of kidney failure in patients with chronic kidney disease (CKD), according to a study published in the European Heart Journal [1] ...

Aims Mineralocorticoid receptor (MR) antagonists improve cardiovascular outcomes in patients with heart failure complicating acute myocardial infarction (AMI) and in chronic heart failure. It is ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

THE lachrymal gland in mammals has acinar tissue leading to ducts lined with columnar epithelium showing no regional differentiation. The Na/K ratio of an established secretion shows no alteration in ...

Credit: Getty Images Investigators report promising results from a phase 2 trial of an investigational aldosterone synthase inhibitor. Combining the aldosterone synthase inhibitor with empagliflozin ...

Please provide your email address to receive an email when new articles are posted on . BI 690517 dose-dependently reduced urine albumin-to-creatine ratio, showing a potential albuminuria reduction.

Mineralys' lorundrostat, a selective aldosterone synthase inhibitor, shows promise in treating resistant hypertension with fewer side effects compared to current MRAs. Upcoming catalysts include ...

Please provide your email address to receive an email when new articles are posted on . Once-daily lorundrostat safely lowered 24-hour systolic BP compared with placebo in a phase 2 trial. A ...