In this study conducted in Taiwan, China, Chung and colleagues identified 48 patients with severe allopurinol-related skin reactions and compared their clinical and genetic features with those of 138 ...

Researchers found independent associations for 2 HLA class I alleles with an increased risk for allopurinol-induced SCAR: HLA-B*58:01 and HLA-A*34:02. HealthDay News — Two human leukocyte antigen (HLA ...

Matched cohort studies revealed infrequent adverse events (AEs) with either treatment, but the number needed to harm for any AE was more than three times higher with colchicine vs NSAIDs. The ...

Trial subgroup analyses support the use of either allopurinol or febuxostat in patients with stage 3 CKD and gout. A prespecified analysis of the STOP-GOUT trial revealed that allopurinol has similar ...

The full CMI on the next page has more details. If you are worried about using this medicine, speak to your doctor or pharmacist. ALLOPURINOL ALPHAPHARM contains the active ingredient allopurinol.