DUBLIN--(BUSINESS WIRE)--Research and Markets (http://www.researchandmarkets.com/research/6prvtz/dyslipidemia) has announced the addition of the "Dyslipidemia Drugs ...

FOSTER CITY, Calif. & SAN DIEGO--(BUSINESS WIRE)-- Mirum Pharmaceuticals, Inc. (NASDAQ: MIRM) and Travere Therapeutics, Inc. (NASDAQ: TVTX) today announced that they have entered into a definitive ...

NEW YORK (Reuters Health) - Colestimide, a resin that binds and eliminates bile acids, seems to be an effective treatment for obesity and type 2 diabetes -- at least in mice -- according to a report ...

Clin Lipidology. 2012;7(6):721-730. Ezetimibe is a selective cholesterol absorption inhibitor that prevents the absorption of dietary and biliary cholesterol through the intestinal wall. The ...

PARIS, FRANCE, 18 November, 2024 Ipsen (Euronext: IPN; ADR: IPSEY) today announced data at the American Association for the Study of Liver Diseases (AASLD) assessing the long-term efficacy and safety ...

(A) The classic bile acid synthesis pathway: cholesterol 7α-hydroxylase (CYP7A1) converts cholesterol to 7α-hydroxycholesterol (7α-HOC). The sterol 12α-hydroxylase (CYP8B1) converts the intermediate ...

The widespread clinical use of statins has contributed to significant reductions in the rate of cardiovascular morbidity and mortality over the past 3 decades, and statins are considered first-line ...

Primary bile acids are synthesized from cholesterol in the liver, which is transformed to cholic acid (CA) through the classical pathway and chenodeoxycholic acid (CDCA) as an alternative pathway.

For the first time, a team of experts from the Technical University of Munich (TUM), RWTH Aachen University, and the German ...

Hepatocellular carcinoma is among the leading causes of tumor-related death, and the liver is among the most common sites of cancer metastasis. Several types of immune cells surveil the liver to ...