Scientists studying a hard-to-treat form of blood cancer called acute myeloid leukemia (AML) have found that a type of treatment—immunotherapy—may help change the environment where cancer cells live, ...

Bone marrow is the spongy tissue located within the hollow center of bones, serving as the primary site for the continuous production of red blood cells, platelets, and white blood cells. Despite its ...

An illustration of bone and bone marrow development. During the process, osteoclasts (cells in blue) expand the marrow cavity by absorbing and removing unnecessary bone. In this study, the team found ...

Researchers at the University of California, Santa Cruz, have identified a key molecule for establishing blood stem cells in their niche within the bone marrow. The findings, reported in the January ...

Scientists at the University of Glasgow developed a bioengineered bone marrow (BM) model that helped them to evaluate potential use of a combined CRISPR-CAR T cell therapy in the treatment of acute ...

Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been hindered by a lack of effective markers and monoclonal antibodies to ...

Schematic diagram illustrating how expansion of bone marrow adipocytes in obesity increases MCP-1 signaling, promotes PD-L1 + immunosuppressive myeloid cells, and enhances osteoclastogenesis, leading ...

Why do some patients with precursors to bone marrow cancer never develop the disease? Researchers from the Department of Forensic Medicine at Aarhus University have discovered that some cells enter a ...