a Adjusted for significant prognostic factors. b RAM+DOC pts stratified by C min,1 quartile (µg/mL) (n = 94 for each): Q1 ≤ 15.7; Q2 > 15.7 ≤ 20.7; Q3 > 20.7 ≤ 27.9; Q4 > 27.9; compared to PL+DOC pts.
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