Scientists at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences have developed a multi-chamber organoid that mirrors the heart’s intricate structure. The human ...

In humans, a specialized mRNA translation circuit predetermines the competence for heart formation at an early stage of embryonic development, a research team at the Center for Molecular Medicine ...

Australian researchers have uncovered a crucial new mechanism that helps explain how the heart's major blood vessels form during early development, and how disruptions to this process can lead to ...

Mechanical cues are key regulators of cardiac development, yet their role in organoid maturation remains underexplored. In a new study, researchers introduce a magnetic torque stimulation (MTS) system ...

A University of Houston pharmacology researcher and expert in cardiac development has identified a new cause of—and repair for—left ventricular non-compaction, also known as spongy heart disease. The ...

Heart disease remains the leading cause of death worldwide, yet progress in understanding and treating cardiac disorders is limited by the shortcomings of existing experimental models. Traditional ...

Patients with therapeutic intensification of pharmacological pressure-unloading therapy had marked improvements in cardiac load, the study found, as demonstrated by reductions in N-terminal pro-B-type ...

New research in Sweden has produced a "blueprint" revealing how the human heart is built during prenatal development. It offers insights that could lead to improved prenatal care and new treatments ...