When cells experience enough chronic stress, they can stop dividing permanently. In this state of cellular limbo, known as ...
Director of the Institute of Biochemistry and Molecular Biology at University Hospital Bonn (UKB) and member of the Transdisciplinary Research Area “Life & Health” at the University of Bonn. The ...
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The enzyme that doesn't act like one: NUDT5 controls DNA building block production through structure, not catalysis
Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules. A central part of this network is folate metabolism, a process that ...
The result is adipocytes accommodating larger lipid droplets – and increasing the size of these fat cells. “This study nudges us a little closer to the clinic by revealing a brand-new handle on how ...
Scientists have developed a novel approach of genome editing to repair muscle stem (satellite) cells, offering new hope for Duchenne muscular dystrophy (DMD) treatment. While adeno-associated virus ...
Researchers from Tokyo Metropolitan University have created a new molecule which carries DNA into biological cells, to treat or vaccinate against illnesses. Many existing options rely on molecules ...
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