Researchers have identified a mechanism by which acetylcholine, a neurotransmitter best known for its role in muscle control and attention, can effectively commandeer serotonin release inside the ...

Acetylcholine "conductors" in the striatum directly trigger serotonin release, offering new insights into the origins of OCD and chemical imbalances.

Before the advent of the amyloid hypothesis in the 1990s, the cholinergic hypothesis offered key clues to the etiology of Alzheimer’s disease. Concentrated in the basal forebrain and projecting ...