The dataset, which the researchers have made available on the Open Reaction Database, is nearly five times as large as the ...

A new cross-coupling reaction weds chiral carboxylic acids, such as proline derivatives, to alkyl iodides while preserving ...

The diarylmethane backbone is a base of molecules relevant for various industrial and especially pharmaceutical applications where they serve as a platform for the discovery of new drugs. One of the ...

Here, we report our discovery and development of a nickel-catalysed enantioselective migratory cross-electrophile coupling reaction of amino alcohol-derived sulfonates with simple alkyl sulfonic ...

In an effort to open the door to new and useful products, chemistry researchers are on the continual lookout for processes ...

Cross-coupling reactions—chemical transformations in which two fragments are joined together—are a valuable tool in the synthesis of organic molecules. Applications range from drug development and ...

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