Double-strand breaks (DSBs) in DNA are challenging to repair. Cells employ at least three DSB-repair mechanisms, with a preference for non-homologous end joining (NHEJ) over homologous recombination ...

Circular RNA (circRNA) has gained significant attention in RNA therapeutics due to its enhanced stability and protein-coding potential. In this study, we present two in vitro RNA circularization ...

Tuberculosis (TB) remains one of the world's most serious public health threats, with approximately one-quarter of the global population infected with Mycobacterium tuberculosis. While most infections ...

Feasibility of consensus molecular subtype classification of colorectal cancer using preoperative biopsy specimens: A prospective pilot study.

RNA exon editing enables replacement of multiple entire exons at kilobase scale, potentially addressing large genes and high allelic heterogeneity common in inherited kidney disorders. Endogenous ...