Unlike nuclear DNA, mitochondrial DNA (mtDNA) is circular in nature and organized as mitochondrial nucleoids comprised of DNA-protein complexes that are distributed in the matrix. It is also inherited ...

A scientific team says it has pinpointed the crucial steps in the beginning of the DNA replication process, including surprising structural details about the enzyme that unzips and splits the double ...

An elusive step in the process of human DNA replication has been observed, for the first time, by scientists. The step, which is crucial for DNA replication in humans and other forms of life, had ...

A team has published pictures at very high atomic resolution of the multi-part protein complex that performs the very first step in the incredibly complex genome-replication dance that occurs when one ...

Activation of initiation of DNA replication occurs at only a subset of replication origins that were previously assembled in the G1 phase of the cell cycle. This is achieved through a highly regulated ...

Cold Spring Harbor, NY - It's a good thing we don't have to think about putting all the necessary pieces in place when one of our trillions of cells needs to duplicate its DNA and then divide to ...