A study published today in the journal Developmental Cell uncovers new insights into how the heart forms during the earliest stages of embryonic development. The research, led by scientists at the ...

An advanced human heart organoid system can be used to model embryonic heart development under pregestational diabetes-like conditions, researchers report. The organoids recapitulate hallmarks of ...

Researchers at the UNC School of Medicine, UNC McAllister Heart Institute, and the UNC Lineberger Comprehensive Cancer Center characterized the expression of thousands of cardiac proteins during eight ...

How do human organs develop and what happens to them when they become diseased? To answer these questions, researchers are increasingly focusing on so-called organoids. These mini-organs, just a few ...

Congenital heart defects are the most common form of human birth defect, but we still don't fully understand what causes them. Previous research had suggested that some heart defects could be ...

Congenital heart defects are the most common form of human birth defect, but we still don’t fully understand what causes them. Previous research had suggested that some heart defects could be ...

Now, in a study in zebrafish and human heart muscle cells, researchers show that a tiny deletion in the A-band of titin — the loss of just nine amino acids out of more than 27,000 to 35,000 amino ...

Scientists at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences have developed a multi-chamber organoid that mirrors the heart’s intricate structure. The human ...

This video shows a 3D confocal reconstruction of an organoid surface, showing blood vessels in green and cardiomyocytes in red. Blue is cell nuclei. An advanced human heart organoid system can be used ...