Post-mortem brain analysis shows decades of alcohol use significantly alter endocannabinoid gene expression in the prefrontal cortex and nucleus accumbens. Increased CB1, reduced CB2, altered GPR55 ...

Chronic alcohol consumption profoundly alters gene expression in key brain regions involved in reward, impulse control, and ...

Plenty of recent research has shown compelling correlations between gut microbiome alterations and mood disorders such as depression. But exactly how bacteria in the gut could be influencing ...

Daily consumption of caffeine is seen as a "normal" addiction, er, habit. It doesn't seem to pose any deleterious health effects, and, tolerance and withdrawal aside, many people can stay on a daily ...

The endocannabinoid system is comprised of various endogenous ligands, their receptors, and a complex enzyme and transporter apparatus. Each of the components of the endocannabinoid system is involved ...

“For decades, scientists and mental health physicians tried to figure out how THC worked on the brain and body,” explained Dr. Paul Song, Chief Medical Officer of Calyx Peak Companies via email. A ...

Stress is a ubiquitous risk factor for the exacerbation and development of affective disorders including major depression and posttraumatic stress disorder. Understanding the neurobiological ...

Currently, in the United States, forty-six states and three territories have some form of a medical cannabis program. This has been a long struggle for advocates, however. Marijuana has been known to ...

La Jolla, California-based Artelo Biosciences, Inc. (Nasdaq: ARTL) recently announced that its Canadian subsidiary, Artelo Biosciences Corporation, is the recipient of a Mitacs Accelerate Grant that ...

“Once your mom admits to using cannabis, it’s tougher to support laws that would put her in jail.” —Amanda Reiman Amanda Reiman is the Vice President of Community Development for Flow Kana, a branded ...

If there aren’t enough reasons already, add more leafy greens to your diet. Research has shown that leafy greens rich with the terpene beta-caryophyllene activate the CB2 receptor in mice models. Beta ...

In 1964, Israeli scientist Raphael Mechoulam isolated tetrahydrocannabinol, or THC, from a cannabis plant. Hundreds of chemicals exist in cannabis, not just the high-inducing THC and supposed-wellness ...