This course aims to provide deepened and widened knowledge of concepts, reactivity, and synthesis in modern organic chemistry. It encompasses: main group chemistry, carbonyl/enol/enolate chemistry, ...

The activation of the α-carbons of carboxylic esters and related carbonyl compounds to generate enolate equivalents as nucleophiles is one of the most powerful strategies in organic synthesis. We ...

Making a quaternary carbon center is tough enough as it is, but that can pale in comparison to making a crowded tertiary center next to it. Caltech’s Brian M. Stoltz, Jan Streuff, and colleagues have ...