Discover the latest articles and news in related subjects. Because mutations in internal residues are not, in most cases, useful for determining specific function(s) of a protein, we directed our ...
The group found that Est3 highly resembles a mammalian telomere-associated protein called TPP1. "This is surprising because TPP1 is not a subunit of the telomerase complex," explained Lundblad, noting ...
Every time your cells divide, the “telomeres,” or caps on the ends of your chromosomes, get a little shorter. Elderly creatures begin to suffer diseases of old age partly because their telomeres have ...
They found that, like several other telomeric proteins, Est3 exhibited an architectural element known as an "OB" fold. Using computer models to scrutinize the fold surface, the group predicted that ...
LA JOLLA, CA — It may take just one or two proteins to polish off a simple cellular task, but life-or-death matters, such as caring for the ends of chromosomes known as telomeres, require interacting ...
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