In the human genome, the fraction of synonymous codons changes monotonically with the GC content of coding sequences: with increasing the GC content the codons that are richer in GC within their ...

Scientists have discovered a new way to suppress mutations that lead to a wide range of genetic disorders. About 15% of mutations that lead to genetic diseases are called nonsense mutations. Aptly ...

Here, we discover potential ‘latent driver’ mutations in cancer genomes. Latent drivers have low frequencies and minor observable translational potential. As such, to date they have escaped ...