Protein function and activity are determined by both their assembly and secondary structure. Abnormalities related to either protein aggregation or secondary structure can lead to neurodegenerative ...
Bivalent metal ions induce formation of α-synuclein fibril polymorphs with different cytotoxicities
Then the Congo red (CR) binding assay was performed to further confirm α-Syn fibril formation and to quantitatively evaluate the formation of the β-sheets during fibrillation. As shown in Fig. 1A, ...
In-situ generation of a hydrogelator from non-assembling precursors offers an effective strategy for preparing supramolecular hydrogel materials with precise spatiotemporal control. These hydrogels ...
A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a new study. The discovery is a ...
A new international study, has revealed insights into the mechanisms underlying radiation damage at the molecular level. The research, published in Nature Chemistry, reveals how extensive, localized ...
Researchers have discovered inorganic nanostructures surrounding deep-ocean hydrothermal vents that are strikingly similar to molecules that make life as we know it possible. These nanostructures are ...
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