Chronic kidney disease silently undermines the immune system, leaving patients dangerously vulnerable to infections that ...

A team of researchers led by Professor Koji Eto (Department of Clinical Application) recently discovered the importance of a microRNA-based regulatory mechanism for enhancing the quality and quantity ...

Platelets play a central role in haemostasis by translating mechanical cues into biochemical responses that ensure rapid arrest of bleeding and restoration of vascular integrity. Upon vascular injury, ...

A collaborative research team led by Dr. Thorsten Schlaeger (Boston Children's Hospital) Emiri Nakamura and Professor Koji Eto (Department of Clinical Application) has identified microtubule (MT) ...

Intravital microscopy image from the liver of a mouse model: a platelet (turquoise) adheres to the inflamed vessel wall (yellow dashed outline) and sheds a long, filamentous membrane extension—a ...

Platelets play an essential role in wound healing. Underproduction can cause devastating bleeding, while overproduction increases the deadly risk of thromboses. Maintaining a constant level of ...

When a vascular injury occurs, platelets in young mice form much smaller blood clots (left) than platelets in old mice (right), where the clot almost blocks the blood vessel. Fluorescence microscopy ...

Together with researchers from University of Oxford, researchers at Karolinska Institutet have demonstrated that a subclass of stem cells that are dedicated to the production of platelets replenish ...

A new computational framework links the metabolic enzyme NNMT to coordinated platelet, neutrophil, and immune exhaustion ...

Researchers have discovered a distinct, secondary population of platelets that appears with aging and have hyperreactive behavior and unique molecular properties, which could make them easier to ...