A new drug combination shows unexpected synergy against liver fibrosis. A new study reveals that using two drugs together ...

Carboxylesterases are a class of enzymes that play a pivotal role in the metabolism of a wide array of endogenous and exogenous compounds. Predominantly expressed in the liver and intestine, these ...

Scientists have found that combining silybin with carvedilol works far better against liver fibrosis than either drug alone.

The liver is the principal site of the body's drug metabolism, so it isn't surprising that drug-induced liver injury (DILI) can occur. However, despite the common use of medications in today's society ...

Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...

Researchers discovered that more than 300 liver genes are under circadian control: Circadian variations affect how much of a drug is available and how effectively the body can break it down. Giving ...

The liver is accountable for metabolizing most medications and is therefore one of the primary tissues affected by adverse drug reactions. Most classes of medicine can cause drug-induced liver injury ...

Liver disease is the new “silent killer” that’s quietly becoming one of the world’s biggest health concerns. The most common type among different kinds of liver diseases, fatty liver disease, is ...

Chronic liver disease gets worse when the liver's immune system stays overactive, resulting in ongoing inflammation and ...