The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained at early life, with implications for understanding and treating immunodeficiency, ...

The miniature models could exponentially accelerate vaccine development, cancer treatment research, and improved health outcomes across a spectrum of diseases. The left image shows the immune organ-on ...

Medical researchers have used animals, particularly mice, to mimic disease and study biological phenomena. The origin of mice as a standard model system for scientific research can extend back to the ...

Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient's immune system to better recognize cancer cells—by using engineered ...

In a recent review published in the European Journal of Immunology, a group of authors summarized current advances, challenges, and future directions in human systems immunology using multi-omics ...

I am lying under a blanket, feeling rough, staring at a bowl of oranges. Every fibre of my being is urging me to devour the lot. I can hear my mum – and medical friends at university – insisting that ...

For most women, the body begins to change dramatically in their 40s or 50s. This transition, known as menopause, is defined ...

A new study has uncovered a previously unknown antiviral defense mechanism in sea anemones, revealing that animals may have ...

Human peadiatric thymus image from the IBEX protein multiplex (44 proteins on the same image) platform. Thymic epithelial cells are labeled with DEC205 (cyan), pan-cytokeratin (purple), keratin 5 (red ...

These miniature immune system models -- known as human immune organoids -- mimic the real-life environment where immune cells learn to recognize and attack harmful invaders and respond to vaccines.

The left image shows the immune organ-on-chip, where the organoids (right) are grown to study the response of human donors. The right image shows development of types of immune cells relevant to the ...