In work suggesting a new approach to treating polycystic kidney disease, a leading cause of kidney failure, researchers were able to block the formation of fluid-filled cysts, the hallmark of the ...

A kidney cyst is a swelling filled with watery fluid that forms on one or both of the kidneys. Kidney cysts are round, have a thin, clear wall and range in size from microscopic to around 5 cm in ...

Kidney cysts occur following inactivation of polycystins in otherwise intact cilia or following complete removal of cilia by inactivation of intraflagellar transport–related proteins. We investigated ...

Figure 2: miR-17∼92 deletion attenuates cyst growth in early-onset ADPKD models. Figure 3: miR-17∼92 deletion attenuates disease progression in long-lived and slow cyst growth models of ADPKD. Figure ...

A drug commonly used to treat diabetes may also retard the growth of fluid-filled cysts of the most common genetic disorder, polycystic kidney disease. Researchers report that pioglitazone appears to ...

Polycystic kidney disease (PKD) is a genetic disease which causes the development of cysts in a patient’s kidneys. It originates from a gene defect in the patient’s deoxyribonucleic acid (DNA) passed ...