LC-MS/MS has been increasingly adopted by clinical laboratories due to the potential it has for increased sensitivity and specificity over more commonly used analytical techniques. However, ...

Researchers found that blood collection tubes from different manufacturers can interfere with LC-MS/MS measurement of serum 25-hydroxyvitamin D [25 (OH)D], a critical preanalytical quality control ...

Figure 1. A schematic representation of a lipid nanoparticle encapsulating mRNA. As this new form of biotechnology makes a leap of progress, so too do the analytical approaches supporting its ...

Biomarkers play an important role in drug development and help in the identification of disease-causing proteins found in blood, urine, body fluids, and tissue samples. The combination of liquid ...

Liquid chromatography-mass spectrometry (LC/MS) is a powerful integrated chemical technique that allows simultaneous separation of components from a mixture and analysis of each component based on ...

LC-MS is used to analyse pharmaceuticals across a variety of stages in their discovery and development. These stages include drug discovery, metabolism studies (in vitro and in vivo), and ...

Chili powder's complex matrix poses challenges for pesticide residue analysis, requiring optimized LC–MS/MS methods for ...

Food allergies are a growing health issue as they become ever more prevalent around the globe. 1 As a reaction to this growth, the European Commission (EC) issued Regulation No. 1169/2011. 2 It sets ...

High-resolution, accurate-mass (HRAM) mass spectrometers (MS) are a class of MS instrumentation with capability to resolve complex sample matrix and to allow identification of compounds by measuring ...