First MYC condensate-modulating small molecule advanced to Development Candidate• Demonstrates potent, selective inhibition of MYC-driven ...

MYC regulates the transcription of thousands of genes required to coordinate a range of cellular processes, including those essential for proliferation, growth, differentiation, apoptosis and ...

Effects of c-Myc overexpression on the DNA damage-induced G2/M checkpoint were studied in finite lifespan, normal human mammary epithelial cells (HMECs). Previously, we showed that c-Myc attenuates G1 ...

A team of researchers at VCU Massey Comprehensive Cancer Center discovered an innovative way to use a drug already approved ...

An international research team has succeeded in deciphering a key mechanism that controls the growth of pancreatic cancers. The scientists identified a potential central mechanism by which cancer ...

In healthy cells, the protein MYC helps guide the process of transcription, in which genetic information is converted from DNA into RNA and, eventually, into proteins. However, the shapeless protein ...

Northwestern Medicine investigators have discovered a new combination approach that may improve the efficacy of MYC inhibitor drugs for treating aggressive and treatment-resistant cancers, according ...

Meet MYC, the shapeless protein responsible for making the majority of human cancer cases worse. Researchers have found a way to rein it in, offering hope for a new era of treatments. Meet MYC, the ...

Scientists have learned that prostate cancers can vary significantly among patients and that there are often differences within each patient's tumor. However, the study published Aug. 28 in Nature ...

Sperm – in theory, you only need one good one to get the job done. Nevertheless, the average pair of human testicles is estimated to crank out about a trillion of these little cells over a lifetime, ...

During an episode of your favorite true crime drama, you’ve probably seen the detective piece together clues with all evidence pointing neatly to “Suspect A”. But there’s something that doesn’t quite ...