A February 2015 report from the Centers for Disease Control and Prevention provided updated estimates of prescription opioid analgesic use among adults ages 20 and over. The authors concluded that ...

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

Am J Health Syst Pharm. 2009;66(11):1020-1030. Participant sex was fairly equally distributed within each study, with the exception of the lower abdominal surgery Phase III study, which had ...

Julie Blendy, professor of pharmacology at University of Pennsylvania’s Perelman School of Medicine, presented her research on the molecular and genetic mechanisms behind opioid use disorders in the ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

Morphine is the most abundant analgesic opiate found in opium and is a potent pain reliever. The drug is used in clinical pain relief but is also used illicitly for recreational purposes among drug ...

The FDA is conducting a workshop to discuss the science (lack thereof, really) of Morphine Milligram Equivalents as it applies to the atrocious CDC 2016 Opioid Prescribing Guidelines. Public comments ...

Opioids are naturally occurring substances that have several effects on the central nervous system that are mainly mediated by opioid receptors. There are three subtypes of this receptor (μ1, μ2 and ...

A little-known morphine-like drug is potentially more potent, longer lasting and less likely to cause constipation than standard morphine, a study has found. The drug also is less likely to cause ...

Opium use for pain relief has a long history. People started using opium around 3500 B.C. Through the ages, it’s been known as a universal cure-all. In 1803, morphine was isolated from opium, making ...

Despite irrefutable pharmacological evidence of the wide range in individuals' metabolism of opioid drugs, states continue to impose "one-size-fits-none" laws. For example, Massachusetts, apparently ...

Am J Health Syst Pharm. 2009;66(11):1020-1030. Certain populations had slight variations in several pharmacokinetic parameters. Body weight differences between men and women most likely caused the 25% ...