In the human genome, the fraction of synonymous codons changes monotonically with the GC content of coding sequences: with increasing the GC content the codons that are richer in GC within their ...

Scientists have discovered a new way to suppress mutations that lead to a wide range of genetic disorders. About 15% of mutations that lead to genetic diseases are called nonsense mutations. Aptly ...

Modern medicine is undergoing a remarkable transformation owing to the rapid progress in gene therapy methods. Through the application of advanced molecular biology technology and enhanced delivery ...

In a recent perspective published in the journal Cell Death and Differentiation, researchers in France, Germany, and Sweden discussed the unique mutational spectrum of the transformation-related ...