Addressing overdoses from “street drugs” containing potent synthetic opioids poses a key challenge when utilizing opioid antagonists. A standard approach to known or suspected opioid overdose includes ...

Combining an opioid antagonist such as naloxone with an alpha 2-adrenergic agonist is a feasible approach for managing opioid withdrawal, results of a new Cochrane review suggest. However, it is ...

Purpose. Published reports on placebo-controlled clinical trials and other studies investigating the use of pure opioid antagonists for the prevention and treatment of opioid-induced pruritus (OIP) ...

MONMOUTH JUNCTION, N.J., Jan. 08, 2026 (GLOBE NEWSWIRE) -- Tris Pharma, Inc. (Tris), a commercial-stage biopharmaceutical company, today announced the acceptance of its peer-reviewed article "The ...

Naloxone, the opioid overdose antidote, is a powerful tool in the overdose crisis, allowing friends, loved ones and even bystanders a way to put a fatal overdose in reverse and bring back breathing.

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while ...

Struggling with alcohol cravings? Naltrexone targets the brain's reward center to minimize drinking urges and reduce harmful ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

When you have a mild headache or muscle ache, an over-the-counter pain reliever is usually enough to make you feel better. But if your pain is more severe, your doctor might recommend something ...