Scientists are racing to redesign how powerful painkillers work, aiming to keep the relief that opioids provide while ...

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

Given how profound an influence opioids have on the world – for better or worse – scientists know surprisingly little about how these drugs actually work. A recent study led by researchers from ...

New research reveals previously unknown ways opioid receptors can function, opening the door to safer pain treatments.

Naloxone, the opioid overdose antidote, is a powerful tool in the overdose crisis, allowing friends, loved ones and even bystanders a way to put a fatal overdose in reverse and bring back breathing.

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Researchers have taken a ...

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was ...

Medications have become our go-to treatments for opioid addiction. Though life-saving, their downsides are underappreciated ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. An international team of ...

Struggling with alcohol cravings? Naltrexone targets the brain's reward center to minimize drinking urges and reduce harmful ...

In the clinical trial, 30 men in India with opioid use disorder were randomly chosen to receive 10 supervised 45-minute yoga ...