SCT800 is a new third-generation recombinant FVIII agent that is undergoing promising preclinical study. This study aimed to investigate the pharmacokinetic and pharmacodynamic profiles of SCT800 in ...

Randomized Phase II/III Trial of Interferon Alfa-2a With and Without 13-cis-Retinoic Acid in Patients With Progressive Metastatic Renal Cell Carcinoma: The European Organisation for Research and ...

When you pop a prescription pill into your mouth, you trust it to address the issue it was meant to fix. But what really happens? How is your body processing the drugs and what happens if the dosage ...

BUFFALO, N.Y. — When you pop a prescription pill into your mouth, you trust it to address the issue it was meant to fix. But what really happens? How is your body processing the drugs and what happens ...

Radiation Therapy for Intracranial Germinoma: Results of the German Cooperative Prospective Trials MAKEI 83/86/89 PURPOSE: To determine the safety, pharmacokinetics, and pharmacodynamic effect of 2-[4 ...

Background. Posaconazole is a triazole with anti-Aspergillus activity. However, little is known about the utility of posaconazole as primary therapy for invasive pulmonary aspergillosis. Methods. An ...

Minimum inhibitory concentrations (MICs) can be very useful in selecting the best antimicrobial agent for a given patient with known culture and susceptibility results. However, to do so effectively, ...

QRL-101, an oral small molecule being developed by QurAlis, was safe and reduced nerve-cell overactivity in ALS patients in ...

In drug discovery, various parameters need to be established in preclinical trials before a pharmaceutical is approved for initial testing on human subjects. Pharmacokinetics is a field of study which ...

An integrated evaluation of the pharmacodynamic and pharmacokinetic properties of a drug is essential for successful translation to the clinic. However, cost-effective methods to measure these ...

Please provide your email address to receive an email when new articles are posted on . In pediatric patients, Anaphylm produced a maximum concentration that “slightly exceeded” the one found in ...