BIOENGINEER

Fungal Killer’s Achilles Heel Found in RNA Splicing Machinery

A conserved Lsm8-exosome module that safeguards RNA splicing fidelity has been revealed as a master switch controlling growth ...
Unite.AI

Illumina Launches SpliceAI2 Model for Splice Variant Interpretation

Illumina introduced SpliceAI2 on October 8, 2026, a genomic AI model from its BioInsight AI Lab that predicts how genetic ...

Akari Therapeutics Expands Intellectual Property Portfolio with PCT Filing for ADC Payload Related to RNA Splicing in Cancers

Patent filing covers PH1 payload’s unique ability to disrupt multiple cancer-driving pathways in addition to its overall ...

The Genome’s Hidden Layer

A study finds that mammalian cells can join RNA from separate genes into functional hybrid proteins, revealing a hidden layer ...
Fred Hutch

RNA “typos” can highlight leukemia cells for immune attack

Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...
Phys.org

AI-driven framework enables precise prediction of RNA splicing and isoform usage

RNA is the means of translating the genetic code embedded in DNA into proteins, which serve as enzymes, transporters, signaling molecules, receptors, structural components, regulators, and ...
Medical Xpress

RNA splicing strategy corrects tumor suppressor gene in neuroendocrine cancers

Neuroendocrine tumors, including small cell lung cancer and neuroendocrine prostate cancer, are very aggressive with high chances of spreading. However, many individuals develop resistance to few ...
Phys.org

Biologists discover a new type of control over RNA splicing

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...
Fred Hutch

Mutant’s partner in crime could be target for future cancer therapy

When you can’t take down the kingpin, go after his accomplices. This strategy may work for cancer as well, according to scientists at Fred Hutch Cancer Center and Memorial Sloan Kettering Cancer ...
Medical Xpress

Alternative RNA splicing tied to schizophrenia-like behaviors in animal models

In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia. The research was conducted by scientists led by LI Ming ...
BIOENGINEER

Fly Study Reveals How the RNA Modifier Mettl16 Shapes Development and Fertility

New research in fruit flies shows that the RNA methyltransferase Mettl16 is dispensable for survival but essential for fertility, acting through targeted m6A deposition and U6-dependent splicing ...
News Medical

LUC7 proteins play crucial role in efficient RNA splicing

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...