Small molecules, tablets, capsules, soft gels, effervescence, gummies, and pills. These are all oral solid dosage (OSD) forms, a term that refers to a final drug product therapy that is ingested ...

Formulating drugs to ensure therapeutic consistency, enable rapid development, and allow for cost-effective scale-up has become increasingly challenging. This is especially true in the context of ...

Bayer inked a deal with Syntegon Technology for access to a novel continuous manufacturing process for oral solid dosage forms. The process uses fluid bed granulation, which yields granules with ...

At the manufacturing level, pharmaceutical manufacturers are leveraging advanced technologies and automation to address challenges such as sample under fill and overfill, detect contaminants and other ...

The hot melt extrusion (HME) process can be employed in the production of a wide range of pharmaceutical dosage forms, including capsules, tablets, lozenges and implants. HME is suitable for both ...

Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

FDA researchers present case studies using soft sensors to predict critical quality attributes and monitor crystallinity and ...

Granulation and agglomeration technology is a popular topic and of growing interest for different industries - and, therefore, academia - as it is such a key process in the manufacture of many solid ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...