Deoxyribonucleic acid (DNA) replication is fundamental to life, yet the precise mechanics of how helicases unwind the genome for replication remain unclear. A recent study published in Nature used ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life. A new study from King ...

Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

Scientists at the University of Leicester have captured the first detailed "molecular movie" showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in ...

BUFFALO, N.Y. – New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...