Figure 1: Active Rac1 enhances mineralocorticoid receptor (MR) transcriptional activity and nuclear translocation. Figure 2: Renal damage, activity of Rho family GTPases and MR signaling in Arhgdia ...
Abiraterone use for prostate cancer can cause mineralocorticoid excess syndrome (MES; eg, hypertension and hypokalemia). Prednisone mitigates these effects; however, the optimal dose level is unclear.
In a recent meta-analysis published in The Lancet, researchers investigated the effect of steroidal and nonsteroidal mineralocorticoid receptor antagonists (MRAs) on patients with heart failure (HF) ...
Impact of the Affordable Care Act and Medicaid Expansion Among Patients With HIV-Associated Aggressive B-Cell Non-Hodgkin Lymphomas Data for 1,410 abiraterone-treated patients from 2011 to 2022 were ...
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