Background Heart auscultation is a widely used and cost-effective clinical tool for detecting valvular heart disease (VHD), ...

Background Chronic kidney disease is common in patients with coronary artery disease (CAD) and can significantly affect drug excretion and efficacy. This study focuses on the effects of modification ...

Background Current risk scores inadequately predict long-term mortality after transcatheter aortic valve replacement (TAVR), ...

Objective To evaluate the association between chocolate intake and incident clinically apparent atrial fibrillation or flutter (AF). Methods The Danish Diet, Cancer, and Health Study is a large ...

Objective Patients with unoperated single ventricle (SV) rarely survive into adulthood with good functional status and may develop Eisenmenger's syndrome (ES). We report outcomes of a 30-year cohort ...

Currently, most international guidelines advocate for risk stratification of acute pulmonary embolism (PE) as a framework to guide treatment decisions. Key prognostic factors for patients with PE ...

Comparative evaluation of biological and mechanical prostheses for aortic valve replacement in a middle-aged population: a population-based cohort study ...

Objective To assess the relationship between fine particulate matter (PM2.5) concentration and ischaemic heart disease (IHD) morbidity and mortality. Methods A time-series study conducted in Beijing ...

Clinical introduction A 75-year-old patient with hypertension and severe aortic stenosis underwent elective coronary angiography that showed mild non-obstructive disease in the mid left anterior ...

For some decades, after the introduction of the head-up tilt test into clinical practice, the clinical presentation of vasovagal syncope (VVS) has been classified as typical (or classical) and ...

Multifactorial management of complex comorbidity followed by heart failure, chronic kidney disease and type 2 diabetes mellitus: the way to overcome missed opportunities (4 March, 2025 ...

Clinical introduction A 49-year-old man presented to the emergency department following sudden onset chest pain with collapse. He was refurbishing his home when he collapsed on the floor with chest ...