Statistically, Lions quarterback Jared Goff is having the best season of his career. On Saturday, I asked 49ers head coach ...

With their playoff hopes dashed, the San Francisco 49ers aim to finish the season on a high note by playing spoiler against ...

George Kittle enters Monday night's meeting with the Detroit Lions just 33 yards shy of another 1,000-yard season that should ...

The San Francisco 49ers are set to host the Detroit Lions at Levi's Stadium in Santa Clara, California, on Monday, December ...

San Francisco 49ers head coach Kyle Shanahan addressed reporters on Saturday following the team's final practice before their ...

Head coach Kyle Shanahan offered an update on Saturday regarding the recovery of San Francisco 49ers wide receiver Brandon ...

The San Francisco 49ers entered Sunday's matchup against the Miami Dolphins without two key offensive contributors: running ...

The NFL's much-discussed new rule against hip-drop tackles has only produced one penalty flag this season, against Carolina's ...

Tight end George Kittle is known for being one of the most upbeat and positive personalities in the San Francisco 49ers ...

The 49ers are set to head into their "Monday Night Football" contest with the Detroit Lions a little worse for the wear, ...

The 49ers will have running back Isaac Guerendo for Monday Night Football. Guerendo, who missed last week's game with a ...

San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...