By design, adaptive randomization increased the number of patients with triple-negative disease who were assigned to receive veliparib–carboplatin, as compared with other experimental regimens.

The adaptive randomization algorithm uses the molecular characteristics of the cancers and incorporates accumulated outcome data to efficiently identify the biomarker signatures of tumor subtypes ...

Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups.

We provide a theoretical template for the comparison of response-adaptive randomization procedures for clinical trials. Using a Taylor expansion of the noncentrality parameter of the usual chi-squared ...

Adaptive randomization could, of course, lead to smaller sample sizes compared with fixed-ratio randomization; however, its role in influencing the sample size of the CC-115 arm in this study was ...

Lanju Zhang, William F. Rosenberger, Response-Adaptive Randomization for Survival Trials: The Parametric Approach, Journal of the Royal Statistical Society. Series C (Applied Statistics), Vol. 56, No.