A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

Single-cell analysis fails to find a functional link between the organization of chromatin domain organization and gene activity.

In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the ...

A principle of DNA synthesis that has dominated biology textbooks for decades could be upended. An enzyme has been discovered ...

Shixin Liu is pioneering new ways of studying the tiny proteins that copy and read DNA in living cells. (Credit: Roshni ...