Protein droplet formation is enhanced by improperly disordered proteins, possibly leading to many types of genetic disease.

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

The results prove the existence of heat-sensitive cellular functions in the nucleolus which deal with the DNA-dependent RNA synthesis. The precise site of action is assumed to involve hydrogen bonds, ...

About half of the tested proteins impaired the function of the nucleolus, resembling the disease mechanism of BPTA syndrome. New explanations for existing diseases ...