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A new mechanism of controlling translation initiation depends on DEAD-box RNA helicases and on RNA structures, including those present in coding sequences.
In a previous study, Jayaram successfully differentiated between coding and non-coding parts of genes based on chemical properties of the DNA sequence (PLoS One, DOI: 10.1371/journal.pone.0012433).
Patrick A. Alexander, Yanan He, Yihong Chen, John Orban, Philip N. Bryan, A Minimal Sequence Code for Switching Protein Structure and Function, Proceedings of the National Academy of Sciences of the ...
In a new paper published in Science, researchers from the company Raina Biosciences have detailed their new AI-based design program, called GEMORNA, which can provide mRNA sequences to be used in a ...
We determined the sequence of the coding region of segment A, coding for the viral proteins (VPs) VP2, VP4, and VP3, of a very virulent (vv) infectious bursal disease virus (IBDV) isolated in Israel ...
DeepSEA, a deep-learning algorithm trained on large-scale chromatin-profiling data, predicts chromatin effects from sequence alone, has single-nucleotide sensitivity and can predict effects of ...
Annogen will functionally annotate tens of thousands of disease-related non-coding sequence variants with the goal of aiding drug discovery ...