BMJ

Fertility in women with rheumatoid arthritis: influence of disease activity and medication

Correspondence to Jenny Brouwer, Department of Rheumatology, Erasmus MC, Room no. Na-609, PO Box 2040, Rotterdam 3000 CA, The Netherlands; j.brouwer.1{at}erasmusmc.nl Objectives Many female rheumatoid ...
BMJ

AB0559 EFFICACY AND SAFETY OF RITUXIMAB IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

1 Ministry of Education, Key Laboratory of Cellular Physiology, Shanxi Medical University, Taiyuan, China 2 Academy of Mircobial Ecology, Shanxi Medical University, Taiyuan, China 1 Ministry of ...
BMJ

Real-life use of the PEXIVAS reduced-dose glucocorticoid regimen in granulomatosis with polyangiitis and microscopic polyangiitis

3 Centre de Recherche en Epidémiologie et Statistiques (CRESS), Unité Inserm 1153, Université Paris Cité, Paris, France ...
BMJ

FRI0693 Fears and misconceptions of women with chronic rheumatic diseases on their journey to motherhood

Background: Recent EULAR ‘Points to Consider’ provide guidance on management and treatment of Women of Childbearing Age (WoCBA) with chronic rheumatic diseases (CRD: RA, axSpA, PsA). However, it is ...
BMJ

Physician global assessment in systemic lupus erythematosus: can we rely on its reliability?

We read with great interest the recent paper by Aranow et al 1 about the impact of laboratory results on scoring of the Physician Global Assessment (PGA) of disease activity in systemic lupus ...
BMJ

Relationship between serum urate and changes in dual-energy CT monosodium urate crystal volume over 1 year in people with gout: an individual participant data analysis

Objectives The dynamics of monosodium urate (MSU) crystal changes across a range of serum urate concentrations in people with gout are unknown. This study aimed to systematically examine the ...
BMJ

Vascular occlusion for optimising the functional improvement in patients with knee osteoarthritis: a randomised controlled trial

Objectives Knee osteoarthritis (KOA) is a leading cause of global disability with conventional exercise yielding only modest improvements. Here we aimed to investigate the benefits of integrating ...
BMJ

Exaggerated neutrophil extracellular trap formation in Kawasaki disease: a key phenomenon behind the outbreak in western countries?

Correspondence to Dr Kiyomi Mizugishi, Department of Hematology, Kyoto University Hospital, Kyoto 606-8507, Japan; kiyomim{at}kuhp.kyoto-u.ac.jp KD is a multisystem vasculitis that primarily affects ...
BMJ

The effect of different durations of remission on damage accrual: results from a prospective monocentric cohort of Caucasian patients

Correspondence to Professor Andrea Doria, Division of Rheumatology, Department of Medicine, University of Padova, Via Giustiniani, 2, Padova 35128, Italy; adoria{at}unipd.it Aim To identify the ...
BMJ

Evidence that autoantibody production may be driven by acute Epstein-Barr virus infection in Sjögren’s disease

Objectives Sjögren’s disease (SD) is an autoimmune disease affecting the exocrine glands that is associated with autoantibodies against Ro60/SS-A, anti-Ro52/TRIM21, La/SS-B and others. We examined the ...
BMJ

OP0307 Efficacy and safety of risankizumab, a selective il-23p19 inhibitor, in patients with active psoriatic arthritis over 24 weeks: results from a phase 2 trial

Background Interleukin-23 (IL-23), a key regulator of multiple effector cytokines, has been implicated in the pathogenesis of psoriatic lesions, synovitis, enthesitis, and bone erosion. Risankizumab ...
BMJ

Protein kinase R is highly expressed in dermatomyositis and promotes interferon-beta-induced muscle damage

Objectives Dermatomyositis (DM) has been consistently linked to the type I interferon (IFN-I) pathway. However, the precise pathogenesis remains incompletely elucidated. We aimed to explore potential ...