Deebo Samuel revealed why San Francisco quarterback Brock Purdy was upset after Sunday's win over the Tampa Bay Buccaneers.

Christian McCaffrey returned to San Francisco 49ers practice on Wednesday with a clean bill of health after making his season ...

Star pass-catcher George Kittle and the San Francisco 49ers face the Seattle Seahawks on Sunday at 4:05 p.m. ET, at Levi’s ...

A handful of players were absent from the first Week 11 practice for the 49ers with four of them being star players.

Kittle injured his hamstring during the 49ers’ Week 10 win over the Tampa Bay Buccaneers. Shanahan told reporters in a press ...

Here are your top 49ers storylines for Wednesday, November 13th.

The San Francisco 49ers earned a hard-fought victory on Sunday against the Tampa Bay Buccaneers, securing back-to-back wins ...

Listen in as players from the 49ers locker room shared their excitement for DB Deommodore Lenoir's five-year contract ...

The San Francisco 49ers are preparing for their Week 11 contest against the Seattle Seahawks on Sunday at Levi's Stadium in ...

Former Super Bowl-winning coach Jon Gruden is looking to jump back into the NFL coaching fray, according to Boomer Esiason.

The San Francisco 49ers overcame a late-game surge by the Tampa Bay Buccaneers to win 23-20 in Week 10. All-Pro running back ...