Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be ...

Researchers suggest modulating intestinal microbiota or antigen-presenting activity of IECs represents new approaches to treating autoimmune neurological disease.

Prize winner’s research reprograms tumor cells to trigger antitumor immunity   Cancer immunotherapies, such as checkpoint ...

The cells that line the inside of the gut may play a key role in triggering inflammation that drives MS, a study found.

How does the gut cause Multiple Sclerosis? New research identifies the MHC II protein in intestinal epithelial cells as the trigger for MS-related neuroinflammation. Discover how gut-primed T cells ...

Multiple sclerosis (MS) is a debilitating neurological disorder caused by malfunctioning immune responses that target the ...

Breakthrough intranasal therapy for allergic rhinitis shows promise in targeting root causes. Learn how nanoparticles could change hayfever treatment.

A single injection of a redesigned immune-stimulating antibody directly into a tumor was linked to shrinkage not only at the ...

Researchers have established a direct experimental link between inflammatory signals in the intestinal lining and the kind of ...

Overcoming efficacy, safety, and manufacturing hurdles through innovative personalized cancer vaccine design ...

Immunomodulatory agents—including defined synthetic compounds, biologics, and selected probiotics/live biotherapeutic approaches—are increasingly being ...