Stepping away from its billions-of-years-old role as a genetic blueprint, DNA is now embarking on a new journey as an active ...

The period between the 1920s and 1950s was a time of significant progress and exciting discoveries in gene therapy history and biomedicine. Groundbreaking advances in understanding inherited DNA and ...

CRISPR is a powerful DNA-editing tool that has underpinned huge advancements in human health care in the last decade. It is a ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

An international team of researchers has taken an important step toward understanding how gene expression is controlled across the human genome. The research is published in the journal Nature. The ...

More than one hundred key genes linked to DNA damage have been uncovered through systematic screening of nearly 1,000 genetically modified mouse lines, in a new study published today (14 February) in ...

A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act like molecular anchors. The work confirms these tags actively silence genes, ...

A new gene-editing technique enables the correction of multiple genetic mutations simultaneously, transforming the prospects for millions living with complex inherited diseases, such as cystic ...

Researchers have found that certain bacteria carry a naturally occurring system, built from repurposed CRISPR components, ...

Genes are segments of DNA (deoxyribonucleic acid) that are located inside every human cell. The DNA inside each cell is tightly coiled in structures called chromosomes. Each chromosome contains a ...