Holger Rune didn't have anything against Jannik Sinner taking a medical timeout but noted that a lengthy break ruined his rhythm. After the world No. 1 started to physically struggle late in the second set of their Australian Open round-of-16 match - the Italian's hands were shaking and his movement was impacted - the Dane won that set and also had the upper hand early in the third set.

Jannik Sinner has achieved his goal by reaching the quarterfinals at the 2025 Australian Open. The world number 1 defeated a very dangerous opponent like Holger Rune in four sets, overcoming a malaise that hit him between the second and third sets and also forced him to leave the court for assistance.

Jannik Sinner is through to the Australian Open quarterfinals after a drama-filled fourth-round win over Holger Rune. World No. 1 Sinner won in four sets, 6-3. 3-6, 6-3, 6-2, but this did not tell the story of a contest defined by illness.