The kidney protection is complicated because ACE inhibitors always increase the creatinine level, making it look like they hurt the kidney. Deep inside the kidney, blood flow to the nephron (the ...

There is a paucity of biomarkers that reliably detect nephrotoxicity. The Predictive Safety Testing Consortium (PSTC) faced several challenges in identifying novel safety biomarkers in the renal ...

The nephrons are the structures of the kidney that filter the blood and reabsorb water and other molecules. Each nephron consists of a tubule and a glomerulus. In this Perspective, the authors explore ...

Sodium bicarbonate is an antacid medication that may help treat metabolic acidosis in people with kidney disease. If a person has kidney disease, it may cause them to develop metabolic acidosis. This ...

DEAR DR. ROACH: I have suffered from high blood pressure since I was a young man in my early 20s. I recently turned 70 years old. My blood pressure has been controlled by various medications. Most ...

“Personalized medicine” denotes the future of disease treatment. This implies that etiologically distinct entities, even if they converge on a common disease pathway, may benefit from differentiated ...

ACE inhibitors lower blood pressure and protect the kidneys by decreasing angiotensin II levels. Vitamin D helps maintain strong bones, but too much can cause issues if not monitored. ARBs block ...

Some medications, including certain antibiotics and NSAIDs, can harm the kidneys if used for too long or in high doses. ACE inhibitors and ARBs are generally safe but can increase the risk of kidney ...