The New England Journal of Medicine10d
CD4+ T-Cell Lymphoma Harboring a Chimeric Antigen Receptor Integration in TP53
Malignant T-cell transformation after chimeric antigen receptor (CAR ... Cell clone sizes that are associated with unique integration sites were quantified with the use of the SonicAbundance ...
New Publication Highlights Unique Properties of ATI-2138, a Potent and Selective Inhibitor of ITK and JAK3
Data Generated to Date Support Potential for Aclaris’ ATI-2138 to Impact Several Human Inflammatory Diseases -WAYNE, Pa., Feb. 12, 2025 ...
Mirror life is a scientific fantasy leading to a dangerous reality. How mirror bacteria could conquer life on Earth
Most major biological molecules, including all proteins, DNA and RNA, point in one direction or another. In other words, they ...
T-knife Therapeutics to Participate in Two Investor Conferences in March
SAN FRANCISCO and BERLIN, Feb. 12, 2025 (GLOBE NEWSWIRE) -- T-knife Therapeutics, Inc., a biopharmaceutical company developing T cell receptor (TCR) engineered T cell therapies (TCR-T) to fight cancer ...
EurekAlert!5d
American Heart Month — Basic scientists seek to uncover the fundamentals of heart disease risk factors
Basic science researchers at the Johns Hopkins University School of Medicine are advancing heart health research by finding ...
Research shows sotagliflozin is the first medication of its kind to significantly reduce both heart attacks and strokes
Sotagliflozin, a drug recently approved by the Food and Drug Administration to treat type 2 diabetes and kidney disease with ...
Mirror life is a scientific fantasy leading to a dangerous reality − a synthetic biologist explains how mirror bacteria could conquer life on Earth
It’s important to note that researchers are likely at least 10 to 30 years away from creating mirror bacteria. On the timescale of a fast-moving field like synthetic biology, a decade is a very long ...
eLife11d
Single-cell sequencing provides clues about the developmental genetic basis of evolutionary adaptations in syngnathid fishes
This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...
News Medical22h
Sensitive CAR expression detection with flow cytometry
By targeting surface markers on cancer cells, engineered synthetic receptors expressed on immune cells can be directed to ...
News Medical on MSN6h
Sotagliflozin could be used to reduce the risk of deadly cardiovascular events, trial shows
Sotagliflozin, a drug recently approved by the Food and Drug Administration to treat type 2 diabetes and kidney disease with additional cardiovascular risk factors, can significantly reduce heart ...
ALZFORUM9d
From the Meninges, Regulatory T Cells Keep Brain Inflammation in Check
Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...
Nature10d
The who, how and where of antigen presentation to B cells
Recognition of specific antigen through the B-cell receptor (BCR ... and they also have a unique strategic role in the transport of antigen to FDCs in the germinal centre. This wide variety ...