A team at UT Southwestern Medical Center has identified a structural trick that lets viruses translate their genetic code inside human cells, even when that code is riddled with “bad” codons the host ...

Genetic medicine has made huge progress over the past two decades. Gene therapy, gene editing, and mRNA treatments are now approved for a growing number of conditions. These approaches focus on fixing ...

Coronaviruses not only use the machinery of the human cells they infect: they modify them to achieve optimal conditions to ...

Genetic diseases are notoriously challenging to treat, especially when each condition requires a tailored approach. With over 10,000 known genetic disorders, developing individual therapies for each ...

Findings reveal coronaviruses exploit stress-linked tRNA modifications, enhancing translation efficiency and offering insights for antiviral drug development.

CEO Sanjay Shukla outlined the company’s strategy to develop new therapies for inflammation and fibrosis based on tRNA synthetase biology during a presentation at the Leerink Partners Global ...

A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly ...

Christine Dunham is a leading expert on the ribosome—an elaborate macro-molecular machine that operates like a factory within ...

A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly ...

CRF awards four global grants to advance CHM research toward new clinical trial endpoints and therapeutic approaches—driving progress toward treatments.

Company scheduled to meet with the FDA in mid-April 2026 to review the results of the Phase 3 EFZO-FIT™ study and determine the path forward for efzofitimod in pulmonary sarcoidosis. Phase 2 ...