The 49ers likely have no intention of playing starter Christian McCaffrey in the preseason, backup Isaac Guerendo is out for ...

The San Francisco 49ers held out a couple of rookies Saturday night against the Denver Broncos in their first preseason game.

Denver Broncos outside linebacker Nik Bonitto had a dominating series against the San Francisco 49ers on Saturday evening.

San Francisco 49ers head coach Kyle Shanahan had some huge praise for Broncos' quartertback Bo Nix after joint practice.

The 49ers say it's the calf injury and not business that kept wide receiver Jauan Jennings out vs. the Denver Broncos.

The 49ers opened their preseason with a 30-9 loss against the Denver Broncos from Levi's Stadium in Santa Clara, Calif. While ...

The 49ers scored a touchdown on their opening series of the preseason, then their defense crumbled in a 30-9 loss against the ...

Nearly 40 players are brand new to the 49ers’ roster and poised to make their debut in Saturday’s preseason opener against ...

"I expect them to be one of the better teams in the league this year," 49ers coach Kyle Shanahan said of the Broncos.

The 49ers released veteran kicker Greg Joseph on Monday, but head coach Kyle Shanahan stopped short of saying that means Jake ...

Both Davis and CJ West started the game at the defensive tackle spots. In limited reps, he got a sack and made three tackles. With how he’s played so far, Davis will likely be one of the starting ...

Although it was the first preseason game and many starters didn't suit up, it still wasn't the result head coach Kyle Shanahan was looking for. After the game, Shanahan was honest ...